As images for the Andres Serrano x Supreme collaboration make their way around the internet, one word continues to crop up: controversial. The underground brand-turned-ubiquitous cool kid streetwear company has teamed up with Serrano – a half Honduran, half Afro-Cuban photographer known for his contentious work – for its latest capsule collection. Serrano uses religious iconography and mixes it with blood, semen, breast milk, and urine.

Piss Christ, Serrano’s most famous work, shows a plastic crucifix immersed in a jar of urine. “At the time I made Piss Christ, I wasn’t trying to get anything across,” Serrano told the Guardian. “In hindsight, I’d say Piss Christ is a reflection of my work, not only as an artist, but as a Christian.” After the 1987 piece went on display, he received hate mail and death threats for years. The last time it was shown in 2011, it was damaged.

Along with Piss Christ, the red-hued Supreme collection will also feature Madonna & Child II and Blood and Semen II. The images are emblazoned on everything from Supreme hoodies to T-shirts to Vans SK8-Hi, Old Skool, and Chukka shoes.

The collection will be available in-store at Supreme’s New York, Los Angeles, London, and Paris locations, as well as online on September 21. As with every Supreme drop, you know the hypebeast-dom will be intense. Peep the collection here.